!!This displayer contains script commands. You should enable JavaScripting within your browser preferences, or use another browser!
USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
Search by
Maps
Select Remote Interfaces
[All Interfaces]
SWISS-2DPAGE
World-2DPAGE Portal
World-2DPAGE Repository
Exclude local DBs
has only effect if a remote
interface is selected
Searching in 'USC-OGP 2-DE database' for entry
matching:
GGCT_HUMAN
USC-OGP 2-DE database
:
GGCT_HUMAN
GGCT_HUMAN
General information about the entry
View entry in simple text format
Entry name
GGCT_HUMAN
Primary accession number
O75223
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Gamma-glutamylcyclotransferase; EC=2.3.2.4; AltName: Full=Cytochrome c-releasing factor 21;.
Gene name
Name=GGCT
Synonyms=C7orf24, CRF21
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
PLATELET_4-5
{PLATELET 4-5}
Homo sapiens (Human)
map experimental info
PLATELET_4-5
MAP LOCATIONS:
SPOT OGP-0221
:
pI=5.00; Mw=20827
UVEAL_MELANOMA_3-10
{UVEAL MELANOMA 3-10}
Homo sapiens (Human)
map experimental info
UVEAL_MELANOMA_3-10
MAP LOCATIONS:
SPOT OGP-1306
:
pI=5.02; Mw=22379
Cross-references
UniProtKB/Swiss-Prot
O75223; GGCT_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
GGCT_HUMAN
Primary accession number
O75223
Secondary accession number(s)
B2RDN0 B8ZZN4 B8ZZR8 Q9BS37
Sequence was last modified on
November 1, 1998 (version 1)
Annotations were last modified on
March 15, 2017 (version 129)
Name and origin of the protein
Description
RecName: Full=Gamma-glutamylcyclotransferase; EC=2.3.2.4; AltName: Full=Cytochrome c-releasing factor 21;
Gene name
Name=GGCT
Synonyms=C7orf24, CRF21
Encoded on
Name=GGCT; Synonyms=C7orf24, CRF21
Keywords
3D-structure
;
Acyltransferase
;
Alternative splicing
;
Complete proteome
;
Phosphoprotein
;
Reference proteome
;
Transferase
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
AK315608; BAG37977.1
; -; mRNA
EMBL
AC005154; -
; NOT_ANNOTATED_CDS; Genomic_DNA
EMBL
CH471073; EAW93950.1
; -; Genomic_DNA
EMBL
CH471073; EAW93952.1
; -; Genomic_DNA
EMBL
CH471073; EAW93953.1
; -; Genomic_DNA
EMBL
BC000625; AAH00625.1
; -; mRNA
EMBL
BC005356; AAH05356.1
; -; mRNA
EMBL
BC013937; AAH13937.1
; -; mRNA
EMBL
BC019243; AAH19243.1
; -; mRNA
CCDS
CCDS5428.1; -. [O75223-1]
; .
CCDS
CCDS56474.1; -. [O75223-3]
; .
CCDS
CCDS56475.1; -. [O75223-2]
; .
CCDS
CCDS56476.1; -. [O75223-4]
; .
RefSeq
NP_001186744.1; NM_001199815.1. [O75223-4]
; .
RefSeq
NP_001186745.1; NM_001199816.1. [O75223-2]
; .
RefSeq
NP_001186746.1; NM_001199817.1. [O75223-3]
; .
RefSeq
NP_076956.1; NM_024051.3. [O75223-1]
; .
UniGene
Hs.530024; -
; .
PDB
2I5T; X-ray
; 2.01 A; A/B=2-188
PDB
2PN7; X-ray
; 2.41 A; A/B=1-188
PDB
2Q53; X-ray
; 2.01 A; A/B=2-188
PDB
2RBH; X-ray
; 2.10 A; A/B=1-188
PDB
3CRY; X-ray
; 1.70 A; A/B=1-188
PDBsum
2I5T; -
; .
PDBsum
2PN7; -
; .
PDBsum
2Q53; -
; .
PDBsum
2RBH; -
; .
PDBsum
3CRY; -
; .
ProteinModelPortal
O75223; -
; .
SMR
O75223; -
; .
BioGrid
122486; 10
; .
IntAct
O75223; 7
; .
STRING
9606.ENSP00000275428; -
; .
iPTMnet
O75223; -
; .
PhosphoSitePlus
O75223; -
; .
BioMuta
GGCT; -
; .
OGP
O75223; -
; .
EPD
O75223; -
; .
MaxQB
O75223; -
; .
PaxDb
O75223; -
; .
PeptideAtlas
O75223; -
; .
PRIDE
O75223; -
; .
DNASU
79017; -
; .
Ensembl
ENST00000005374; ENSP00000005374
; ENSG00000006625. [O75223-2]; .
Ensembl
ENST00000275428; ENSP00000275428
; ENSG00000006625. [O75223-1]; .
Ensembl
ENST00000409144; ENSP00000386610
; ENSG00000006625. [O75223-3]; .
Ensembl
ENST00000409390; ENSP00000387235
; ENSG00000006625. [O75223-4]; .
GeneID
79017; -
; .
KEGG
hsa:79017; -
; .
UCSC
uc003tba.4; human. [O75223-1]
; .
CTD
79017; -
; .
DisGeNET
79017; -
; .
GeneCards
GGCT; -
; .
HGNC
HGNC:21705; GGCT
; .
HPA
HPA020735; -
; .
HPA
HPA029914; -
; .
MIM
137170; gene
; .
neXtProt
NX_O75223; -
; .
OpenTargets
ENSG00000006625; -
; .
PharmGKB
PA162389392; -
; .
eggNOG
KOG4059; Eukaryota
; .
eggNOG
ENOG4111IGG; LUCA
; .
GeneTree
ENSGT00500000044921; -
; .
HOGENOM
HOG000008049; -
; .
HOVERGEN
HBG050922; -
; .
InParanoid
O75223; -
; .
KO
K00682; -
; .
OMA
RCPHSPM; -
; .
OrthoDB
EOG091G0NMM; -
; .
PhylomeDB
O75223; -
; .
TreeFam
TF314378; -
; .
BRENDA
2.3.2.4; 2681
; .
Reactome
R-HSA-174403; Glutathione synthesis and recycling
; .
ChiTaRS
GGCT; human
; .
EvolutionaryTrace
O75223; -
; .
GenomeRNAi
79017; -
; .
PRO
PR:O75223; -
; .
Proteomes
UP000005640; Chromosome 7
; .
Bgee
ENSG00000006625; -
; .
CleanEx
HS_GGCT; -
; .
ExpressionAtlas
O75223; baseline and differential
; .
Genevisible
O75223; HS
; .
GO
GO:0005829; C:cytosol
; IDA:UniProtKB; .
GO
GO:0070062; C:extracellular exosome
; IDA:UniProtKB; .
GO
GO:0003839; F:gamma-glutamylcyclotransferase activity
; IDA:UniProtKB; .
GO
GO:0042803; F:protein homodimerization activity
; IDA:UniProtKB; .
GO
GO:0006750; P:glutathione biosynthetic process
; TAS:Reactome; .
GO
GO:0001836; P:release of cytochrome c from mitochondria
; IMP:UniProtKB; .
CDD
cd06661; GGCT_like
; 1; .
Gene3D
3.10.490.10; -
; 1; .
InterPro
IPR017939; G-Glutamylcylcotransferase
; .
InterPro
IPR013024; GGCT-like
; .
PANTHER
PTHR12935; PTHR12935
; 1; .
SUPFAM
SSF110857; SSF110857
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
[
Home
]